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    BMCBI
    2007
    200views more  BMCBI 2007»
    Assessment of algorithms for high throughput detection of genomic copy number variation in oligonucleotide microarray data
    13 years 11 months ago
    Assessment of algorithms for high throughput detection of genomic copy number variation in oligonucleotide microarray data
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    Background: Genomic deletions and duplications are important in the pathogenesis of diseases, such as cancer and mental retardation, and have recently been shown to occur frequent...
    Ágnes Baross, Allen D. Delaney, H. Irene Li...
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    BMCBI
    2007
    97views more  BMCBI 2007»
    A verification protocol for the probe sequences of Affymetrix genome arrays reveals high probe accuracy for studies in mouse, hu
    13 years 11 months ago
    A verification protocol for the probe sequences of Affymetrix genome arrays reveals high probe accuracy for studies in mouse, hu
    Download  gbb.eldoc.ub.rug.nl
    Background: The Affymetrix GeneChip technology uses multiple probes per gene to measure its expression level. Individual probe signals can vary widely, which hampers proper interp...
    Rudi Alberts, Peter Terpstra, Menno Hardonk, Leoni...
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    BMCBI
    2007
    159views more  BMCBI 2007»
    sIR: siRNA Information Resource, a web-based tool for siRNA sequence design and analysis and an open access siRNA database
    13 years 11 months ago
    sIR: siRNA Information Resource, a web-based tool for siRNA sequence design and analysis and an open access siRNA database
    Download  www.biomedcentral.com
    Background: RNA interference has revolutionized our ability to study the effects of altering the expression of single genes in mammalian (and other) cells through targeted knockdo...
    Jyoti K. Shah, Harold R. Garner, Michael A. White,...
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    BMCBI
    2006
    156views more  BMCBI 2006»
    Bayesian models for pooling microarray studies with multiple sources of replications
    13 years 11 months ago
    Bayesian models for pooling microarray studies with multiple sources of replications
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    Background: Biologists often conduct multiple but different cDNA microarray studies that all target the same biological system or pathway. Within each study, replicate slides with...
    Erin M. Conlon, Joon J. Song, Jun S. Liu
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    BMCBI
    2006
    112views more  BMCBI 2006»
    Assessment of the relationship between pre-chip and post-chip quality measures for Affymetrix GeneChip expression data
    13 years 11 months ago
    Assessment of the relationship between pre-chip and post-chip quality measures for Affymetrix GeneChip expression data
    Download  www.biomedcentral.com
    Background: Gene expression microarray experiments are expensive to conduct and guidelines for acceptable quality control at intermediate steps before and after the samples are hy...
    Lesley Jones, Darlene R. Goldstein, Gareth P. Hugh...
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