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149
Voted
BIOINFORMATICS
2007
15 years 3 months ago
2007
Motivation: Protein–protein complexes are known to play key roles in many cellular processes. However, they are often not accessible to experimental study because of their low s...
137
Voted
BIOINFORMATICS
2007
15 years 3 months ago
2007
Biological pathways provide significant insights on the interaction mechanisms of molecules. Presently, many essential pathways still remain unknown or incomplete for newly sequen...
155
Voted
BMCBI
2007
15 years 3 months ago
2007
Background: Detection of short, subtle conserved motif regions within a set of related DNA or amino acid sequences can lead to discoveries about important regulatory domains such ...
124
Voted
BMCBI
2007
15 years 3 months ago
2007
Background: As a consequence of the evolutionary process, data collected from related species tend to be similar. This similarity by descent can obscure subtler signals in the dat...
142
Voted
BMCBI
2007
15 years 3 months ago
2007
Background: The existence of negative correlations between degrees of interacting proteins is being discussed since such negative degree correlations were found for the large-scal...