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135
Voted
BMCBI
2006
15 years 3 months ago
2006
Background: The imprint of natural selection on gene sequences is often difficult to detect. A plethora of methods have been devised to detect genetic changes due to selective pro...
126
Voted
BMCBI
2006
15 years 3 months ago
2006
Background: Proteomics is the study of the proteome, and is critical to the understanding of cellular processes. Two central and related tasks of proteomics are protein identifica...
126
Voted
BMCBI
2006
15 years 3 months ago
2006
Background: The main processing pathway for MHC class I ligands involves degradation of proteins by the proteasome, followed by transport of products by the transporter associated...
138
Voted
BMCBI
2006
15 years 3 months ago
2006
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
140
Voted
BMCBI
2006
15 years 3 months ago
2006
Background: Accurate methods for extraction of meaningful patterns in high dimensional data have become increasingly important with the recent generation of data types containing ...