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147
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BMCBI
2006
95views more  BMCBI 2006»
15 years 3 months ago
Estimate haplotype frequencies in pedigrees
Background: Haplotype analysis has gained increasing attention in the context of association studies of disease genes and drug responsivities over the last years. The potential us...
Qiangfeng Zhang, YuZhong Zhao, Guoliang Chen, Yun ...
116
Voted
BMCBI
2006
161views more  BMCBI 2006»
15 years 3 months ago
Comparative genomics in cyprinids: common carp ESTs help the annotation of the zebrafish genome
Background: Automatic annotation of sequenced eukaryotic genomes integrates a combination of methodologies such as ab-initio methods and alignment of homologous genes and/or prote...
Alan Christoffels, Richard Bartfai, Hamsa Srinivas...
131
Voted
BMCBI
2006
192views more  BMCBI 2006»
15 years 3 months ago
Analysis of circular genome rearrangement by fusions, fissions and block-interchanges
Background: Analysis of genomes evolving via block-interchange events leads to a combinatorial problem of sorting by block-interchanges, which has been studied recently to evaluat...
Chin Lung Lu, Yen-Lin Huang, Tsui Ching Wang, Hsie...
148
Voted
BMCBI
2006
103views more  BMCBI 2006»
15 years 3 months ago
Statistical inference of chromosomal homology based on gene colinearity and applications to Arabidopsis and rice
Background: The identification of chromosomal homology will shed light on such mysteries of genome evolution as DNA duplication, rearrangement and loss. Several approaches have be...
Xiyin Wang, Xiaoli Shi, Zhe Li, Qihui Zhu, Lei Kon...
131
Voted
BMCBI
2006
116views more  BMCBI 2006»
15 years 3 months ago
Whole genome association mapping by incompatibilities and local perfect phylogenies
Background: With current technology, vast amounts of data can be cheaply and efficiently produced in association studies, and to prevent data analysis to become the bottleneck of ...
Thomas Mailund, Søren Besenbacher, Mikkel H...
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