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BMCBI
2007
135views more  BMCBI 2007»
13 years 9 months ago
LIMPIC: a computational method for the separation of protein MALDI-TOF-MS signals from noise
Background: Mass spectrometry protein profiling is a promising tool for biomarker discovery in clinical proteomics. However, the development of a reliable approach for the separat...
Dante Mantini, Francesca Petrucci, Damiana Pierago...
BMCBI
2007
133views more  BMCBI 2007»
13 years 9 months ago
AGGRESCAN: a server for the prediction and evaluation of "hot spots" of aggregation in polypeptides
Background: Protein aggregation correlates with the development of several debilitating human disorders of growing incidence, such as Alzheimer's and Parkinson's disease...
Oscar Conchillo-Solé, Natalia S. de Groot, ...
BMCBI
2007
159views more  BMCBI 2007»
13 years 9 months ago
Detecting differential expression in microarray data: comparison of optimal procedures
Background: Many procedures for finding differentially expressed genes in microarray data are based on classical or modified t-statistics. Due to multiple testing considerations, ...
Elena Perelman, Alexander Ploner, Stefano Calza, Y...
CC
2008
Springer
133views System Software» more  CC 2008»
13 years 9 months ago
Hardness Amplification via Space-Efficient Direct Products
We prove a version of the derandomized Direct Product lemma for deterministic space-bounded algorithms. Suppose a Boolean function g : {0, 1}n {0, 1} cannot be computed on more th...
Venkatesan Guruswami, Valentine Kabanets
COR
2008
99views more  COR 2008»
13 years 9 months ago
Genetic local search for multicast routing with pre-processing by logarithmic simulated annealing
Over the past few years, several local search algorithms have been proposed for various problems related to multicast routing in the off-line mode. We describe a population-based ...
Mohammed S. Zahrani, Martin J. Loomes, James A. Ma...
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