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BMCBI
2006
213views more  BMCBI 2006»
15 years 4 months ago
CoXpress: differential co-expression in gene expression data
Background: Traditional methods of analysing gene expression data often include a statistical test to find differentially expressed genes, or use of a clustering algorithm to find...
Michael Watson
BMCBI
2006
205views more  BMCBI 2006»
15 years 4 months ago
Application of Petri net based analysis techniques to signal transduction pathways
Background: Signal transduction pathways are usually modelled using classical quantitative methods, which are based on ordinary differential equations (ODEs). However, some diffic...
Andrea Sackmann, Monika Heiner, Ina Koch
BMCBI
2006
115views more  BMCBI 2006»
15 years 4 months ago
The accuracy of several multiple sequence alignment programs for proteins
Background: There have been many algorithms and software programs implemented for the inference of multiple sequence alignments of protein and DNA sequences. The "true" ...
Paulo A. S. Nuin, Zhouzhi Wang, Elisabeth R. M. Ti...
BMCBI
2006
76views more  BMCBI 2006»
15 years 4 months ago
Coloring the Mu transpososome
Background: Tangle analysis has been applied successfully to study proteins which bind two segments of DNA and can knot and link circular DNA. We show how tangle analysis can be e...
Isabel K. Darcy, Jeff Chang, Nathan Druivenga, Col...
BMCBI
2006
89views more  BMCBI 2006»
15 years 4 months ago
ORENZA: a web resource for studying ORphan ENZyme activities
Background: Despite the current availability of several hundreds of thousands of amino acid sequences, more than 36% of the enzyme activities (EC numbers) defined by the Nomenclat...
Olivier Lespinet, Bernard Labedan