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162
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BMCBI
2010
126views more  BMCBI 2010»
15 years 1 months ago
Systematic integration of experimental data and models in systems biology
Background: The behaviour of biological systems can be deduced from their mathematical models. However, multiple sources of data in diverse forms are required in the construction ...
Peter Li, Joseph O. Dada, Daniel Jameson, Irena Sp...
158
Voted
BMCBI
2010
161views more  BMCBI 2010»
15 years 1 months ago
Application of Wavelet Packet Transform to detect genetic polymorphisms by the analysis of inter-Alu PCR patterns
Background: The analysis of Inter-Alu PCR patterns obtained from human genomic DNA samples is a promising technique for a simultaneous analysis of many genomic loci flanked by Alu...
Maurizio Cardelli, Matteo Nicoli, Armando Bazzani,...
140
Voted
BMCBI
2010
100views more  BMCBI 2010»
15 years 1 months ago
New insights into protein-protein interaction data lead to increased estimates of the S. cerevisiae interactome size
Background: As protein interactions mediate most cellular mechanisms, protein-protein interaction networks are essential in the study of cellular processes. Consequently, several ...
Laure Sambourg, Nicolas Thierry-Mieg
138
Voted
BMCBI
2010
142views more  BMCBI 2010»
15 years 1 months ago
Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis
Background: High-throughput profiling of DNA methylation status of CpG islands is crucial to understand the epigenetic regulation of genes. The microarray-based Infinium methylati...
Pan Du, Xiao Zhang, Chiang-Ching Huang, Nadereh Ja...
149
Voted
DEBU
2010
152views more  DEBU 2010»
15 years 1 months ago
Implementing an Append-Only Interface for Semiconductor Storage
Solid-state disks are currently based on NAND flash and expose a standard disk interface. To accommodate limitations of the medium, solid-state disk implementations avoid rewritin...
Colin W. Reid, Philip A. Bernstein