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RECOMB
2006
Springer
14 years 10 months ago
Predicting Experimental Quantities in Protein Folding Kinetics Using Stochastic Roadmap Simulation
Abstract. This paper presents a new method for studying protein folding kinetics. It uses the recently introduced Stochastic Roadmap Simulation (SRS) method to estimate the transit...
Tsung-Han Chiang, Mehmet Serkan Apaydin, Douglas L...
RECOMB
2006
Springer
14 years 10 months ago
Leveraging Information Across HLA Alleles/Supertypes Improves Epitope Prediction
We present a model for predicting HLA class I restricted CTL epitopes. In contrast to almost all other work in this area, we train a single model on epitopes from all HLA alleles a...
David Heckerman, Carl Myers Kadie, Jennifer Listga...
RECOMB
2006
Springer
14 years 10 months ago
CONTRAlign: Discriminative Training for Protein Sequence Alignment
In this paper, we present CONTRAlign, an extensible and fully automatic framework for parameter learning and protein pairwise sequence alignment using pair conditional random field...
Chuong B. Do, Samuel S. Gross, Serafim Batzoglou
RECOMB
2006
Springer
14 years 10 months ago
Structural Alignment of Pseudoknotted RNA
In this paper, we address the problem of discovering novel non-coding RNA (ncRNA) using primary sequence, and secondary structure conservation, focusing on ncRNA families with pseu...
Banu Dost, Buhm Han, Shaojie Zhang, Vineet Bafna
RECOMB
2006
Springer
14 years 10 months ago
A Patient-Gene Model for Temporal Expression Profiles in Clinical Studies
Abstract. Pharmacogenomics and clinical studies that measure the temporal expression levels of patients can identify important pathways and biomarkers that are activated during dis...
Naftali Kaminski, Ziv Bar-Joseph