The loss of previously established genes has been proposed as a major force in evolutionary change. While the sequencing of many new species offers the opportunity to identify case...
Gene duplication has long been recognized as a major force in genome evolution and has recently been recognized as an important source of individual variation. For many years the o...
Jin Jun, Paul Ryvkin, Edward Hemphill, Ion I. Mand...
Since the discovery of the "Philadelphia chromosome" in chronic myelogenous leukemia in 1960, there is an ongoing intensive research of chromosomal aberrations in cancer....
The transcriptional regulatory sequences in metazoan genomes often consist of multiple cis-regulatory modules (CRMs). Each CRM contains locally enriched occurrences of binding site...
A key problem of interest to biologists and medical researchers is the selection of a subset of queries or treatments that provide maximum utility for a population of targets. For ...
Delbert Dueck, Brendan J. Frey, Nebojsa Jojic, Vla...