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CMPB
2010
97views more  CMPB 2010»
13 years 7 months ago
A ligand predication tool based on modeling and reasoning with imprecise probabilistic knowledge
Ligand prediction has been driven by a fundamental desire to understand more about how biomolecules recognize their ligands and by the commercial imperative to develop new drugs. ...
Weiru Liu, Anbu Yue, David J. Timson
WSPI
2004
13 years 10 months ago
Ontology: The Discipline and the Tool
Abstract. The fields of philosophy and informatics entertain two somewhat different conceptions of ontology. Philosophical ontology is a branch of metaphysics dating back at least ...
Doug Mayhew, Dirk Siebert
BMCBI
2008
109views more  BMCBI 2008»
13 years 9 months ago
MetaFIND: A feature analysis tool for metabolomics data
Background: Metabolomics, or metabonomics, refers to the quantitative analysis of all metabolites present within a biological sample and is generally carried out using NMR spectro...
Kenneth Bryan, Lorraine Brennan, Padraig Cunningha...
BMCBI
2008
148views more  BMCBI 2008»
13 years 9 months ago
StAR: a simple tool for the statistical comparison of ROC curves
Background: As in many different areas of science and technology, most important problems in bioinformatics rely on the proper development and assessment of binary classifiers. A ...
Ismael A. Vergara, Tomás Norambuena, Evandr...
BMCBI
2008
195views more  BMCBI 2008»
13 years 9 months ago
Goldsurfer2 (Gs2): A comprehensive tool for the analysis and visualization of genome wide association studies
Background: Genome wide association (GWA) studies are now being widely undertaken aiming to find the link between genetic variations and common diseases. Ideally, a well-powered G...
Fredrik Pettersson, Andrew P. Morris, Michael R. B...