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BMCBI
2007
15 years 4 months ago
2007
Background: Regulation of gene expression is relevant to many areas of biology and medicine, in the study of treatments, diseases, and developmental stages. Microarrays can be use...
127
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BMCBI
2007
15 years 4 months ago
2007
Background: In a previous study, we demonstrated that some essential proteins from pathogenic organisms contained sizable insertions/deletions (indels) when aligned to human prote...
140
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BMCBI
2007
15 years 4 months ago
2007
Background: An important and yet rather neglected question related to bioinformatics predictions is the estimation of the amount of data that is needed to allow reliable predictio...
130
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BMCBI
2007
15 years 4 months ago
2007
Background: In practice many biological time series measurements, including gene microarrays, are conducted at time points that seem to be interesting in the biologist's opin...
135
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BMCBI
2007
15 years 4 months ago
2007
Background: In the context of genomic association studies, for which a large number of statistical tests are performed simultaneously, the local False Discovery Rate (lFDR), which...