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BMCBI
2007
13 years 9 months ago
2007
Background: The problem of protein structure prediction consists of predicting the functional or native structure of a protein given its linear sequence of amino acids. This probl...
BMCBI
2008
13 years 9 months ago
2008
Background: Target identification is important for modern drug discovery. With the advances in the development of molecular docking, potential binding proteins may be discovered b...
BMCBI
2008
13 years 9 months ago
2008
Background: The variety of DNA microarray formats and datasets presently available offers an unprecedented opportunity to perform insightful comparisons of heterogeneous data. Cro...
BMCBI
2006
2006
On single and multiple models of protein families for the detection of remote sequence relationships
13 years 9 months ago
Background: The detection of relationships between a protein sequence of unknown function and a sequence whose function has been characterised enables the transfer of functional a...
BMCBI
2006
13 years 9 months ago
2006
Background: Raw data normalization is a critical step in microarray data analysis because it directly affects data interpretation. Most of the normalization methods currently used...