Recent advances in next generation sequencing are providing a number of large whole-genome sequence datasets stemming from globally distributed disease occurrences. This offers an...
Adrienne Breland, Karen Schlauch, Mehmet Hadi Gune...
Biclustering is a very popular method to identify hidden co-regulation patterns among genes. There are numerous biclustering algorithms designed to undertake this challenging task...
Recent studies suggest that the mammalian genomes can be subdivided in segments within which there is limited haplotype diversity. Understanding the distribution and structure of ...
Jeremy W. Wang, Kyle J. Moore, Qi Zhang, Fernando ...
Network-based genome-wide association studies (NWAS) utilize the molecular interactions between genes and functional pathways in biomarker identification. This study presents a no...
Ying-Wooi Wan, Swetha Bose, James Denvir, Nancy La...
As a metabolic network reaches from a state to a steady state, a subset of its fluxes gradually change. The sequence of intermediate states, called the dynamic state, shows the pa...
Growing sequencing and assembly efforts have been met by the advances in high throughput machines. However, the presence of massive amounts of repeats and transposons complicates ...
Nirmalya Bandyopadhyay, A. Mark Settles, Tamer Kah...
A major bottleneck in high-throughput protein crystallography is producing protein-structure models from an electrondensity map. In previous work, we developed Acmi, a probabilist...