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BCB
2010
166views Bioinformatics» more  BCB 2010»
13 years 6 months ago
Fast graph approaches to measure influenza transmission across geographically distributed host types
Recent advances in next generation sequencing are providing a number of large whole-genome sequence datasets stemming from globally distributed disease occurrences. This offers an...
Adrienne Breland, Karen Schlauch, Mehmet Hadi Gune...
BCB
2010
138views Bioinformatics» more  BCB 2010»
13 years 6 months ago
Comparative analysis of biclustering algorithms
Biclustering is a very popular method to identify hidden co-regulation patterns among genes. There are numerous biclustering algorithms designed to undertake this challenging task...
Doruk Bozdag, Ashwin S. Kumar, Ümit V. &Ccedi...
BCB
2010
150views Bioinformatics» more  BCB 2010»
13 years 6 months ago
REAL: an efficient REad ALigner for next generation sequencing reads
Kimon Frousios, Costas S. Iliopoulos, Laurent Mouc...
BCB
2010
489views Bioinformatics» more  BCB 2010»
13 years 6 months ago
ReFHap: a reliable and fast algorithm for single individual haplotyping
Jorge Duitama, Thomas Huebsch, Gayle McEwen, Eun-K...
BCB
2010
161views Bioinformatics» more  BCB 2010»
13 years 6 months ago
Genome-wide compatible SNP intervals and their properties
Recent studies suggest that the mammalian genomes can be subdivided in segments within which there is limited haplotype diversity. Understanding the distribution and structure of ...
Jeremy W. Wang, Kyle J. Moore, Qi Zhang, Fernando ...
BCB
2010
127views Bioinformatics» more  BCB 2010»
13 years 6 months ago
A novel network model for molecular prognosis
Network-based genome-wide association studies (NWAS) utilize the molecular interactions between genes and functional pathways in biomarker identification. This study presents a no...
Ying-Wooi Wan, Swetha Bose, James Denvir, Nancy La...
BCB
2010
150views Bioinformatics» more  BCB 2010»
13 years 6 months ago
Enzymatic target identification with dynamic states
As a metabolic network reaches from a state to a steady state, a subset of its fluxes gradually change. The sequence of intermediate states, called the dynamic state, shows the pa...
Bin Song, Sanjay Ranka, Tamer Kahveci
BCB
2010
13 years 6 months ago
Semi-supervised sequence classification using abstraction augmented Markov models
Cornelia Caragea, Adrian Silvescu, Doina Caragea, ...
BCB
2010
156views Bioinformatics» more  BCB 2010»
13 years 6 months ago
RepFrag: a graph based method for finding repeats and transposons from fragmented genomes
Growing sequencing and assembly efforts have been met by the advances in high throughput machines. However, the presence of massive amounts of repeats and transposons complicates ...
Nirmalya Bandyopadhyay, A. Mark Settles, Tamer Kah...
BCB
2010
140views Bioinformatics» more  BCB 2010»
13 years 6 months ago
Guiding belief propagation using domain knowledge for protein-structure determination
A major bottleneck in high-throughput protein crystallography is producing protein-structure models from an electrondensity map. In previous work, we developed Acmi, a probabilist...
Ameet Soni, Craig A. Bingman, Jude W. Shavlik