RECOMB
2010
Springer
13 years 9 months ago
2010
Springer
Abstract. Emerging research demonstrates the potential of proteinprotein interaction (PPI) networks in uncovering the mechanistic bases of cancers, through identification of intera...
RECOMB
2010
Springer
13 years 9 months ago
2010
Springer
Immense amounts of raw instrument data (i.e., images of fluorescence) are currently being generated using ultra high-throughput sequencing platforms. An important computational cha...
RECOMB
2010
Springer
13 years 9 months ago
2010
Springer
Abstract. Recent genome sequencing studies have shown that the somatic mutations that drive cancer development are distributed across a large number of genes. This mutational heter...
RECOMB
2010
Springer
13 years 9 months ago
2010
Springer
In this work we consider an inference task that biologists are very good at: deciphering biological processes by bringing together knowledge that has been obtained by experiments u...
RECOMB
2010
Springer
13 years 9 months ago
2010
Springer
RECOMB
2010
Springer
13 years 9 months ago
2010
Springer
Abstract. One of the critical stages in drug development is the identification of potential side effects for promising drug leads. Large scale clinical experiments aimed at discove...
CIBCB
2007
IEEE
13 years 9 months ago
2007
IEEE
—In metabolic engineering it is difficult to identify which set of genetic manipulations will result in a microbial strain that achieves a desired production goal, due to the co...
ECCB
2005
IEEE
13 years 9 months ago
2005
IEEE
CIBCB
2006
IEEE
13 years 9 months ago
2006
IEEE
In recent years, unsupervised gene (feature) selection has become an integral part of microarray analysis because of the large number of genes and complexity in biological systems....
CIBCB
2005
IEEE
13 years 9 months ago
2005
IEEE
—Metabolic pathways are crucial to our understanding of biology. The speed at which new organisms are being sequenced is outstripping our ability to experimentally determine thei...