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WABI
2009
Springer
14 years 6 months ago
Quantifying Systemic Evolutionary Changes by Color Coding Confidence-Scored PPI Networks
Phuong Dao, Alexander Schönhuth, Fereydoun Ho...
WABI
2009
Springer
117views Bioinformatics» more  WABI 2009»
14 years 6 months ago
A Simulation Study Comparing Supertree and Combined Analysis Methods Using SMIDGen
Background: Supertree methods comprise one approach to reconstructing large molecular phylogenies given multi-marker datasets: trees are estimated on each marker and then combined...
M. Shel Swenson, François Barbançon,...
WABI
2009
Springer
155views Bioinformatics» more  WABI 2009»
14 years 6 months ago
A Markov Classification Model for Metabolic Pathways
Background: This paper considers the problem of identifying pathways through metabolic networks that relate to a specific biological response. Our proposed model, HME3M, first ide...
Timothy Hancock, Hiroshi Mamitsuka
WABI
2009
Springer
142views Bioinformatics» more  WABI 2009»
14 years 6 months ago
Back-Translation for Discovering Distant Protein Homologies
Background: Frameshift mutations in protein-coding DNA sequences produce a drastic change in the resulting protein sequence, which prevents classic protein alignment methods from ...
Marta Gîrdea, Laurent Noé, Gregory Ku...
WABI
2009
Springer
156views Bioinformatics» more  WABI 2009»
14 years 6 months ago
Phylogenetic Comparative Assembly
Recent high throughput sequencing technologies are capable of generating a huge amount of data for bacterial genome sequencing projects. Although current sequence assemblers succes...
Peter Husemann, Jens Stoye
WABI
2009
Springer
162views Bioinformatics» more  WABI 2009»
14 years 6 months ago
Aligning Biomolecular Networks Using Modular Graph Kernels
Comparative analysis of biomolecular networks constructed using measurements from different conditions, tissues, and organisms offer a powerful approach to understanding the stru...
Fadi Towfic, M. Heather West Greenlee, Vasant Hona...
WABI
2009
Springer
130views Bioinformatics» more  WABI 2009»
14 years 6 months ago
Linear-Time Protein 3-D Structure Searching with Insertions and Deletions
It becomes more and more important to search for similar structures from molecular 3-D structure databases in the structural biology of the post genomic era. Two molecules are said...
Tetsuo Shibuya, Jesper Jansson, Kunihiko Sadakane
WABI
2009
Springer
129views Bioinformatics» more  WABI 2009»
14 years 6 months ago
biRNA: Fast RNA-RNA Binding Sites Prediction
We present biRNA, a novel algorithm for prediction of binding sites between two RNAs based on minimization of binding free energy. Similar to RNAup approach [30], we assume the bin...
Hamidreza Chitsaz, Rolf Backofen, Süleyman Ce...
WABI
2009
Springer
102views Bioinformatics» more  WABI 2009»
14 years 6 months ago
A Tree Based Method for the Rapid Screening of Chemical Fingerprints
Background: The fingerprint of a molecule is a bitstring based on its structure, constructed such that structurally similar molecules will have similar fingerprints. Molecular fin...
Thomas G. Kristensen, Jesper Nielsen, Christian N....
WABI
2009
Springer
132views Bioinformatics» more  WABI 2009»
14 years 6 months ago
mpscan: Fast Localisation of Multiple Reads in Genomes
Abstract. With Next Generation Sequencers, sequence based transcriptomic or epigenomic assays yield millions of short sequence reads that need to be mapped back on a reference geno...
Eric Rivals, Leena Salmela, Petteri Kiiskinen, Pet...