The emergence of high-throughput technologies for measuring biological systems has introduced problems for data interpretation that must be addressed for proper inference. First, ...
Biological knowledge can be inferred from three major levels of information: molecules, organisms and ecologies. Bioinformatics is an established field that has made significant a...
It is now almost15 years since the publication of the first paper on text mining in the genomics domain, and decades since the first paper on text mining in the medical domain. En...
Pierre Zweigenbaum, Dina Demner-Fushman, Hong Yu, ...
The collection of multiple genome-scale datasets is now routine, and the frontier of research in systems biology has shifted accordingly. Rather than clustering a single dataset t...
Balaji S. Srinivasan, Nigam H. Shah, Jason Flannic...
The application of informatics to neuroscience goes far beyond ‘traditional’ bioinformatics modalities such as DNA sequences. In this review, we describe how informatics is be...
The contribution of transposable elements (TEs) to genome structure and evolution as well as their impact on genome sequencing, assembly, annotation and alignment has generated in...
An overview is presented of the construction and use of algebraic partition functions to represent the equilibrium statistical mechanics of multimolecular complexes and their acti...
Mathematical modelling is increasingly used to get insights into the functioning of complex biological networks. In this context, Petri nets (PNs) have recently emerged as a promi...