In the post-genomic era, the organization of genes into networks has played an important role in characterizing the functions of individual genes and the interplay between them. I...
Erliang Zeng, Giri Narasimhan, Lisa Schneper, Kala...
Even after an experimentally prepared gene expression data set has been pre-processed to account for variations in the microarray technology, there may be inconsistencies between ...
We propose a novel approach for predicting protein functions of an organism by coupling sequence homology and PPI data between two (or more) species with multifunctional Gene Onto...
Antonina Mitrofanova, Vladimir Pavlovic, Bud Mishr...
Flow cytometry technique produces large, multidimensional datasets of properties of individual cells that are helpful for biomedical science and clinical research. This paper expl...
Lin Liu, Li Xiong, James J. Lu, Kim M. Gernert, Vi...
Many characteristics of functional synthetic siRNAs have been identified. Our three-phase algorithm was developed to design siRNA on a wholegenome scale based on these characteris...
Mapping B-cell epitopes plays an important role in vaccine design, immunodiagnostic tests, and antibody production. Because the experimental determination of B-cell epitopes is ti...
Using microarray technology for genetic analysis in biological experiments requires computationally intensive tools to interpret results. The main objective here is to develop a â...
Saira Ali Kazmi, Yoo-Ah Kim, Baikang Pei, Ravi Nor...
— Protein sequence motifs information is crucial to the analysis of biologically significant regions. The conserved regions have the potential to determine the role of the protei...
Alternative splicing is a mechanism for generating different gene transcripts (called isoforms) from the same genomic sequence. Finding alternative splicing events experimentally ...
Background: Gene expression signatures in the mammalian brain hold the key to understanding neural development and neurological disease. Researchers have previously used voxelatio...
Li An, Hongbo Xie, Mark H. Chin, Zoran Obradovic, ...