BMCBI
2004
13 years 11 months ago
2004
Background: Two of the mostly unsolved but increasingly urgent problems for modern biologists are a) to quickly and easily analyse protein structures and b) to comprehensively min...
BMCBI
2004
13 years 11 months ago
2004
Background: RNA secondary structure prediction methods based on probabilistic modeling can be developed using stochastic context-free grammars (SCFGs). Such methods can readily co...
BMCBI
2004
13 years 11 months ago
2004
Background: Allelic-loss studies record data on the loss of genetic material in tumor tissue relative to normal tissue at various loci along the genome. As the deletion of a tumor...
BMCBI
2004
13 years 11 months ago
2004
Background: An increasing number of researchers have released novel RNA structure analysis and prediction algorithms for comparative approaches to structure prediction. Yet, indep...
BMCBI
2004
13 years 11 months ago
2004
Background: Polymorphic tandem repeat typing is a new generic technology which has been proved to be very efficient for bacterial pathogens such as B. anthracis, M. tuberculosis, ...
BMCBI
2004
13 years 11 months ago
2004
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
BMCBI
2004
13 years 11 months ago
2004
Background: Metabolic pathway analysis has been recognized as a central approach to the structural analysis of metabolic networks. The concept of elementary (flux) modes provides ...
BMCBI
2004
13 years 11 months ago
2004
Background: Mutations in rpoB, the gene encoding the subunit of DNA-dependent RNA polymerase, are associated with rifampin resistance in Mycobacterium tuberculosis. Several studi...
BMCBI
2004
13 years 11 months ago
2004
