BMCBI
2010
13 years 11 months ago
2010
Background: Many protein structures determined in high-throughput structural genomics centers, despite their significant novelty and importance, are available only as PDB depositi...
BMCBI
2010
13 years 11 months ago
2010
Background: In high-dimensional data analysis such as differential gene expression analysis, people often use filtering methods like fold-change or variance filters in an attempt ...
BMCBI
2010
13 years 11 months ago
2010
Background: Cluster analysis, and in particular hierarchical clustering, is widely used to extract information from gene expression data. The aim is to discover new classes, or su...
BMCBI
2010
13 years 11 months ago
2010
Background: Searching a database of protein structures for matches to a query structure, or occurrences of a structural motif, is an important task in structural biology and bioin...
BMCBI
2010
13 years 11 months ago
2010
Background: The system-level dynamics of many molecular interactions, particularly protein-protein interactions, can be conveniently represented using reaction rules, which can be...
BMCBI
2010
13 years 11 months ago
2010
BMCBI
2010
13 years 11 months ago
2010
BMCBI
2010
13 years 11 months ago
2010
Background: The protein-coding regions (coding exons) of a DNA sequence exhibit a triplet periodicity (TP) due to fact that coding exons contain a series of three nucleotide codon...
BMCBI
2010
13 years 11 months ago
2010
Background: Surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI) is a proteomics tool for biomarker discovery and other high throughput applicatio...