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BMCBI
2010
110views more  BMCBI 2010»
13 years 10 months ago
Improvements to previous algorithms to predict gene structure and isoform concentrations using Affymetrix Exon arrays
Background: Exon arrays provide a way to measure the expression of different isoforms of genes in an organism. Most of the procedures to deal with these arrays are focused on gene...
Miguel A. Anton, Ander Aramburu, Angel Rubio
BMCBI
2010
153views more  BMCBI 2010»
13 years 10 months ago
DiffCoEx: a simple and sensitive method to find differentially coexpressed gene modules
Background: Large microarray datasets have enabled gene regulation to be studied through coexpression analysis. While numerous methods have been developed for identifying differen...
Bruno M. Tesson, Rainer Breitling, Ritsert C. Jans...
BMCBI
2010
91views more  BMCBI 2010»
13 years 10 months ago
Washing scaling of GeneChip microarray expression
Background: Post-hybridization washing is an essential part of microarray experiments. Both the quality of the experimental washing protocol and adequate consideration of washing ...
Hans Binder, Knut Krohn, Conrad J. Burden
BMCBI
2010
76views more  BMCBI 2010»
13 years 11 months ago
Validation and characterization of DNA microarray gene expression data distribution and associated moments
Background: The data from DNA microarrays are increasingly being used in order to understand effects of different conditions, exposures or diseases on the modulation of the expres...
Reuben Thomas, Luis de la Torre, Xiaoqing Chang, S...
BMCBI
2010
113views more  BMCBI 2010»
13 years 11 months ago
Probabilistic Principal Component Analysis for Metabolomic Data
Background: Data from metabolomic studies are typically complex and high-dimensional. Principal component analysis (PCA) is currently the most widely used statistical technique fo...
Gift Nyamundanda, Lorraine Brennan, Isobel Claire ...
BMCBI
2010
108views more  BMCBI 2010»
13 years 11 months ago
iGTP: A software package for large-scale gene tree parsimony analysis
Background: The ever-increasing wealth of genomic sequence information provides an unprecedented opportunity for large-scale phylogenetic analysis. However, species phylogeny infe...
Ruchi Chaudhary, Mukul S. Bansal, André Weh...
BMCBI
2010
80views more  BMCBI 2010»
13 years 11 months ago
Sampling the conformation of protein surface residues for flexible protein docking
Background: The problem of determining the physical conformation of a protein dimer, given the structures of the two interacting proteins in their unbound state, is a difficult on...
Patricia Francis-Lyon, Shengyin Gu, Joel Hass, Nin...
BMCBI
2010
62views more  BMCBI 2010»
13 years 11 months ago
Speeding up tandem mass spectrometry-based database searching by longest common prefix
Chen Zhou, Hao Chi, Leheng Wang, You Li, Yan-Jie W...