Transcriptional attenuation at E.coli’s tryptophan operon is a prime example of RNA-mediated gene regulation. In this paper, we present a discrete stochastic model for this pheno...
Biomodel engineering is the science of designing, constructing and analyzing computational models of biological systems. It forms a systematic and powerful extension of earlier mat...
Rainer Breitling, Robin Donaldson, David R. Gilber...
In this chapter we take a look at the application of replication techniques for building scalable distributed systems. Unlike using replication for attaining dependability, replica...
Abstract The chapter studies how to provide clients with access to a replicated object that is logically indistinguishable from accessing a single yet highly available object. We s...
In this chapter, we discuss a widely used fault-tolerant data replication model called virtual synchrony. The model responds to two kinds of needs. First, there is the practical qu...
Abstract The consensus problem has recently emerged as a major interest in systems conferences, yet the systems community tends to ignore most of the large body of theory on this s...
An important question in genome evolution is whether there exist fragile regions (rearrangement hotspots) where chromosomal rearrangements are happening over and over again. Althou...