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BMCBI
2010
110views more  BMCBI 2010»
13 years 10 months ago
Improvements to previous algorithms to predict gene structure and isoform concentrations using Affymetrix Exon arrays
Background: Exon arrays provide a way to measure the expression of different isoforms of genes in an organism. Most of the procedures to deal with these arrays are focused on gene...
Miguel A. Anton, Ander Aramburu, Angel Rubio
BMCBI
2006
79views more  BMCBI 2006»
13 years 11 months ago
The effects of multiple features of alternatively spliced exons on the KA/KS ratio test
Background: The evolution of alternatively spliced exons (ASEs) is of primary interest because these exons are suggested to be a major source of functional diversity of proteins. ...
Feng-Chi Chen, Trees-Juen Chuang
BMCBI
2006
111views more  BMCBI 2006»
13 years 11 months ago
Using ESTs to improve the accuracy of de novo gene prediction
Background: ESTs are a tremendous resource for determining the exon-intron structures of genes, but even extensive EST sequencing tends to leave many exons and genes untouched. Ge...
Chaochun Wei, Michael R. Brent
ISMB
1994
14 years 23 days ago
An Improved System for Exon Recognition and Gene Modeling in Human DNA Sequence
A new version of the GRAIL system (Uberbacher and Mural, 1991; Mural et al., 1992; Uberbacher et al., 1993), called GRAILII, has recently been developed (Xu et al., 1994). GRAILII...
Yin Xu, J. Ralph Einstein, Richard J. Mural, Manes...
ISMB
1997
14 years 24 days ago
Inferring Gene Structures in Genomic Sequences Using Pattern Recognition and Expressed Sequence Tags
Abstract.) Ying Xu, Richard J. MuraF, and Edward C. Uberbacher Computer Science and Mathematics Division and tLife Sciences Division Computational methods for gene identification ...
Ying Xu, Richard J. Mural, Edward C. Uberbacher
GECCO
2009
Springer
173views Optimization» more  GECCO 2009»
14 years 6 months ago
Creating regular expressions as mRNA motifs with GP to predict human exon splitting
Low correlation between mRNA concentrations measured at different locations for the same exon show many current Ensembl exon definitions are incomplete. Automatically created pa...
William B. Langdon, Joanna Rowsell, Andrew P. Harr...