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BMCBI
2004
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13 years 11 months ago
Improving the scaling normalization for high-density oligonucleotide GeneChip expression microarrays
Background: Normalization is an important step for microarray data analysis to minimize biological and technical variations. Choosing a suitable approach can be critical. The defa...
Chao Lu
BMCBI
2006
100views more  BMCBI 2006»
13 years 11 months ago
Chromosomal patterns of gene expression from microarray data: methodology, validation and clinical relevance in gliomas
Background: Expression microarrays represent a powerful technique for the simultaneous investigation of thousands of genes. The evidence that genes are not randomly distributed in...
Federico E. Turkheimer, Federico Roncaroli, Benoit...
BMCBI
2006
122views more  BMCBI 2006»
13 years 11 months ago
A multivariate prediction model for microarray cross-hybridization
Background: Expression microarray analysis is one of the most popular molecular diagnostic techniques in the post-genomic era. However, this technique faces the fundamental proble...
Yian A. Chen, Cheng-Chung Chou, Xinghua Lu, Elizab...
BMCBI
2010
130views more  BMCBI 2010»
13 years 11 months ago
Analysis of DNA strand-specific differential expression with high density tiling microarrays
Background: DNA microarray technology allows the analysis of genome structure and dynamics at genome-wide scale. Expression microarrays (EMA) contain probes for annotated open rea...
Luis Quintales, Mar Sánchez, Francisco Ante...