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COMBREX (http://combrex.bu.edu) is a project to increase the speed of the functional annotation of new bacterial and archaeal genomes. It consists of a database of functional pred...
Richard J. Roberts, Yi-Chien Chang, Zhenjun Hu, Jo...
Background: Models for the simulation of metabolic networks require the accurate prediction of enzyme function. Based on a genomic sequence, enzymatic functions of gene products a...
Constantin Bannert, A. Welfle, C. aus dem Spring, ...
Background: Assignment of function to new molecular sequence data is an essential step in genomics projects. The usual process involves similarity searches of a given sequence aga...
Liisa B. Koski, Michael W. Gray, B. Franz Lang, Ge...
Background: Two of the main objectives of the genomic and post-genomic era are to structurally and functionally annotate genomes which consists of detecting genes' position a...
Background: Information obtained from diverse data sources can be combined in a principled manner using various machine learning methods to increase the reliability and range of k...
Bolan Linghu, Evan S. Snitkin, Dustin T. Holloway,...
Background: One of the most challenging aspects of biomolecular systems is the understanding of the coevolution in and among the molecule(s). A complete, theoretical picture of th...
Mixture models represent results of gene expression cluster analysis in a more natural way than ’hard’ partitions. This is also true for the representation of gene labels, such...