Background: Genetic association studies have been used to map disease-causing genes. A newly introduced statistical method, called exhaustive haplotype association study, analyzes...
Background: Millions of single nucleotide polymorphisms have been identified as a result of the human genome project and the rapid advance of high throughput genotyping technology...
Wei Yu, Anja Wulf, Tiebin Liu, Muin J. Khoury, Mar...
Background: Synthesis of data from published human genetic association studies is a critical step in the translation of human genome discoveries into health applications. Although...
Wei Yu, Melinda Clyne, Siobhan M. Dolan, Ajay Yesu...
The purpose of this review is to focus on the three most important themes in genetic association studies using randomly selected patients (case, affected) and normal samples (cont...