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BMCBI
2011
13 years 2 months ago
New Words in Human Mutagenesis
Background: The substitution rates within different nucleotide contexts are subject to varying levels of bias. The most well known example of such bias is the excess of C to T (C ...
Alexander Y. Panchin, Sergey I. Mitrofanov, Andrei...
ISAMI
2010
13 years 8 months ago
Employing Compact Intra-genomic Language Models to Predict Genomic Sequences and Characterize Their Entropy
Probabilistic models of languages are fundamental to understand and learn the profile of the subjacent code in order to estimate its entropy, enabling the verification and predicti...
Sérgio A. D. Deusdado, Paulo Carvalho
BMCBI
2005
102views more  BMCBI 2005»
13 years 10 months ago
Genomic multiple sequence alignments: refinement using a genetic algorithm
Background: Genomic sequence data cannot be fully appreciated in isolation. Comparative genomics
Chunlin Wang, Elliot J. Lefkowitz
BMCBI
2008
220views more  BMCBI 2008»
13 years 11 months ago
Gene prediction in metagenomic fragments: A large scale machine learning approach
Background: Metagenomics is an approach to the characterization of microbial genomes via the direct isolation of genomic sequences from the environment without prior cultivation. ...
Katharina J. Hoff, Maike Tech, Thomas Lingner, Rol...
BMCBI
2007
89views more  BMCBI 2007»
13 years 11 months ago
Comparing segmentations by applying randomization techniques
Background: There exist many segmentation techniques for genomic sequences, and the segmentations can also be based on many different biological features. We show how to evaluate ...
Niina Haiminen, Heikki Mannila, Evimaria Terzi
BMCBI
2008
132views more  BMCBI 2008»
13 years 11 months ago
The Average Mutual Information Profile as a Genomic Signature
Background: Occult organizational structures in DNA sequences may hold the key to understanding functional and evolutionary aspects of the DNA molecule. Such structures can also p...
Mark Bauer, Sheldon M. Schuster, Khalid Sayood
ISMB
1997
14 years 5 days ago
Inferring Gene Structures in Genomic Sequences Using Pattern Recognition and Expressed Sequence Tags
Abstract.) Ying Xu, Richard J. MuraF, and Edward C. Uberbacher Computer Science and Mathematics Division and tLife Sciences Division Computational methods for gene identification ...
Ying Xu, Richard J. Mural, Edward C. Uberbacher
CSB
2003
IEEE
110views Bioinformatics» more  CSB 2003»
14 years 4 months ago
Statistical Inference for Well-ordered Structures in Nucleotide Sequences
Distinct, local structures are frequently correlated with functional RNA elements involved in posttranscriptional regulation of gene expression. Discovery of microRNAs (miRNAs) su...
Shu-Yun Le, Jih-H. Chen, Jacob V. Maizel
RECOMB
2010
Springer
14 years 5 months ago
Genomic DNA k-mer Spectra: Models and Modalities
Background: The empirical frequencies of DNA k-mers in whole genome sequences provide an interesting perspective on genomic complexity, and the availability of large segments of g...
Benny Chor, David Horn, Nick Goldman, Yaron Levy, ...