BIOINFORMATICS
2005
13 years 11 months ago
2005
Motivation: Genetic analysis of HIV-1 is important not only for vaccine development, but also to guide treatment strategies, track the emergence of new viral variants and ensure t...
BMCBI
2010
13 years 11 months ago
2010
Background: HIV-1 targets human cells expressing both the CD4 receptor, which binds the viral envelope glycoprotein gp120, as well as either the CCR5 (R5) or CXCR4 (X4) co-recepto...
BMCBI
2010
13 years 11 months ago
2010
Background: Human Immunodeficiency Virus type 1 (HIV-1), the causative agent of Acquired Immune Deficiency Syndrome (AIDS), exhibits very high genetic diversity with different var...
APBC
2004
14 years 28 days ago
2004
Mutation in HIV-1 is extremely rapid, a consequence of a low-fidelity viral reverse transcription process. The envelope gene has been shown to accumulate substitutions at a rate o...
GECCO
2005
Springer
14 years 5 months ago
2005
Springer
Researchers of HIV-1 are today, still unable to determine exactly the biological mechanisms that cause AIDS. Various mechanisms have been hypothesized and their existences have be...