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BMCBI
2011
13 years 6 months ago
Outer membrane proteins can be simply identified using secondary structure element alignment
Background: Outer membrane proteins (OMPs) are frequently found in the outer membranes of gram-negative bacteria, mitochondria and chloroplasts and have been found to play diverse...
Ren-Xiang Yan, Zhen Chen, Ziding Zhang
BMCBI
2005
114views more  BMCBI 2005»
13 years 11 months ago
A new decoding algorithm for hidden Markov models improves the prediction of the topology of all-beta membrane proteins
Background: Structure prediction of membrane proteins is still a challenging computational problem. Hidden Markov models (HMM) have been successfully applied to the problem of pre...
Piero Fariselli, Pier Luigi Martelli, Rita Casadio
BMCBI
2006
105views more  BMCBI 2006»
13 years 11 months ago
Prediction of protein submitochondria locations by hybridizing pseudo-amino acid composition with various physicochemical featur
Background: Knowing the submitochondria localization of a mitochondria protein is an important step to understand its function. We develop a method which is based on an extended v...
Pufeng Du, Yanda Li
BMCBI
2010
125views more  BMCBI 2010»
13 years 11 months ago
Active machine learning for transmembrane helix prediction
Background: About 30% of genes code for membrane proteins, which are involved in a wide variety of crucial biological functions. Despite their importance, experimentally determine...
Hatice U. Osmanbeyoglu, Jessica A. Wehner, Jaime G...
CIBCB
2009
IEEE
14 years 16 days ago
Improved prediction of trans-membrane spans in proteins using an artificial neural network
Tools for the identification of trans-membrane spans from the protein sequence are widely used in the experimental community. Computational structural biology seeks to increase the...
Julia Koehler, Ralf Mueller, Jens Meiler
ISBI
2007
IEEE
14 years 5 months ago
Perceptual Grouping of Membrane Signals in Cell-Based Assays
Membrane proteins organize themselves in a linear fashion where adjacent cells are attached together along the basal-lateral region. Their intensity distributions are often hetero...
Hang Chang, Kumari L. Andarawewa, Ju Han, Mary Hel...
FBIT
2007
IEEE
14 years 5 months ago
Classification of Cell Membrane Proteins
Membrane proteins are an important class of proteins that serve as channels, receptors, and energy transducers in a cell membrane. Knowledge of a given type of cell membrane prote...
Seyed Koosha Golmohammadi, Lukasz A. Kurgan, Brend...