Prediction of protein submitochondria locations by hybridizing pseudo-amino acid composition with various physicochemical featur

Background: Knowing the submitochondria localization of a mitochondria protein is an important step to understand its function. We develop a method which is based on an extended version of pseudo-amino acid composition to predict the protein localization within mitochondria. This work goes one step further than predicting protein subcellular location. We also try to predict the membrane protein type for mitochondrial inner membrane proteins. Results: By using leave-one-out cross validation, the prediction accuracy is 85.5% for inner

• Type: Journal
• Year: 2006
• Where: BMCBI
• Authors: Pufeng Du, Yanda Li
• Keywords: BMCBI 2006, Membrane Proteins, Mitochondria Protein, Proteins