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BMCBI
2011
13 years 6 months ago
Properties of Metabolic Graphs: Biological Organization or Representation Artifacts?
Background: Standard graphs, where each edge links two nodes, have been extensively used to represent the connectivity of metabolic networks. It is based on this representation th...
Wanding Zhou, Luay Nakhleh
ISVC
2010
Springer
13 years 10 months ago
Visual Network Analysis of Dynamic Metabolic Pathways
We extend our previous work on the exploration of static metabolic networks to evolving, and therefore dynamic, pathways. We apply our visualization software to data from a simulat...
Markus Rohrschneider, Alexander Ullrich, Andreas K...
BMCBI
2004
120views more  BMCBI 2004»
13 years 11 months ago
Clustering under the line graph transformation: application to reaction network
Background: Many real networks can be understood as two complementary networks with two kind of nodes. This is the case of metabolic networks where the first network has chemical ...
Jose C. Nacher, Nobuhisa Ueda, Takuji Yamada, Mino...
BMCBI
2007
115views more  BMCBI 2007»
13 years 11 months ago
Correlation between structure and temperature in prokaryotic metabolic networks
Background: In recent years, an extensive characterization of network structures has been made in an effort to elucidate design principles of metabolic networks, providing valuabl...
Kazuhiro Takemoto, Jose C. Nacher, Tatsuya Akutsu
BMCBI
2006
127views more  BMCBI 2006»
13 years 11 months ago
Construction of phylogenetic trees by kernel-based comparative analysis of metabolic networks
Background: To infer the tree of life requires knowledge of the common characteristics of each species descended from a common ancestor as the measuring criteria and a method to c...
Sok June Oh, Je-Gun Joung, Jeong Ho Chang, Byoung-...
BMCBI
2006
101views more  BMCBI 2006»
13 years 11 months ago
Hierarchical modularity of nested bow-ties in metabolic networks
Background: The exploration of the structural topology and the organizing principles of genomebased large-scale metabolic networks is essential for studying possible relations bet...
Jing Zhao, Hong Yu, Jianhua Luo, Zhi-Wei Cao, Yi-X...
BMCBI
2006
118views more  BMCBI 2006»
13 years 11 months ago
Low degree metabolites explain essential reactions and enhance modularity in biological networks
Background: Recently there has been a lot of interest in identifying modules at the level of genetic and metabolic networks of organisms, as well as in identifying single genes an...
Areejit Samal, Shalini Singh, Varun Giri, Sandeep ...
BMCBI
2006
125views more  BMCBI 2006»
13 years 11 months ago
Algebraic comparison of metabolic networks, phylogenetic inference, and metabolic innovation
Metabolic networks are naturally represented as directed hypergraphs in such a way that metabolites are nodes and enzyme-catalyzed reactions form (hyper)edges. The familiar operat...
Christian V. Forst, Christoph Flamm, Ivo L. Hofack...
BMCBI
2007
129views more  BMCBI 2007»
13 years 11 months ago
Integrated network reconstruction, visualization and analysis using YANAsquare
Background: Modeling of metabolic networks includes tasks such as network assembly, network overview, calculation of metabolic fluxes and testing the robustness of the network. Re...
Roland Schwarz, Chunguang Liang, Christoph Kaleta,...
BMCBI
2008
153views more  BMCBI 2008»
13 years 11 months ago
Estimating the size of the solution space of metabolic networks
Background: Cellular metabolism is one of the most investigated system of biological interactions. While the topological nature of individual reactions and pathways in the network...
Alfredo Braunstein, Roberto Mulet, Andrea Pagnani