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    BMCBI
    2007
    153views more  BMCBI 2007»
    Analysis of nanopore detector measurements using Machine-Learning methods, with application to single-molecule kinetic analysis
    13 years 11 months ago
    Analysis of nanopore detector measurements using Machine-Learning methods, with application to single-molecule kinetic analysis
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    Background: A nanopore detector has a nanometer-scale trans-membrane channel across which a potential difference is established, resulting in an ionic current through the channel ...
    Matthew Landry, Stephen Winters-Hilt
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    BMCBI
    2007
    115views more  BMCBI 2007»
    A novel, fast, HMM-with-Duration implementation - for application with a new, pattern recognition informed, nanopore detector
    13 years 11 months ago
    A novel, fast, HMM-with-Duration implementation - for application with a new, pattern recognition informed, nanopore detector
    Download  www.biomedcentral.com
    Background: Hidden Markov Models (HMMs) provide an excellent means for structure identification and feature extraction on stochastic sequential data. An HMM-with-Duration (HMMwD) ...
    Stephen Winters-Hilt, Carl Baribault
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    BMCBI
    2007
    103views more  BMCBI 2007»
    Nanopore-based kinetics analysis of individual antibody-channel and antibody-antigen interactions
    13 years 11 months ago
    Nanopore-based kinetics analysis of individual antibody-channel and antibody-antigen interactions
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    Background: The UNO/RIC Nanopore Detector provides a new way to study the binding and conformational changes of individual antibodies. Many critical questions regarding antibody f...
    Stephen Winters-Hilt, Eric Morales, Iftekhar Amin,...
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