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BMCBI
2007
157views more  BMCBI 2007»
13 years 11 months ago
Statistical learning of peptide retention behavior in chromatographic separations: a new kernel-based approach for computational
Background: High-throughput peptide and protein identification technologies have benefited tremendously from strategies based on tandem mass spectrometry (MS/MS) in combination wi...
Nico Pfeifer, Andreas Leinenbach, Christian G. Hub...
BMCBI
2008
115views more  BMCBI 2008»
13 years 11 months ago
PARPST: a PARallel algorithm to find peptide sequence tags
Background: Protein identification is one of the most challenging problems in proteomics. Tandem mass spectrometry provides an important tool to handle the protein identification ...
Sara Brunetti, Elena Lodi, Elisa Mori, Maria Stell...
BMCBI
2008
107views more  BMCBI 2008»
13 years 11 months ago
A machine learning approach to explore the spectra intensity pattern of peptides using tandem mass spectrometry data
Background: A better understanding of the mechanisms involved in gas-phase fragmentation of peptides is essential for the development of more reliable algorithms for high-throughp...
Cong Zhou, Lucas D. Bowler, Jianfeng Feng
BMCBI
2010
117views more  BMCBI 2010»
13 years 11 months ago
Better score function for peptide identification with ETD MS/MS spectra
Background: Tandem mass spectrometry (MS/MS) has become the primary way for protein identification in proteomics. A good score function for measuring the match quality between a p...
Xiaowen Liu, Baozhen Shan, Lei Xin, Bin Ma
SIGIR
2009
ACM
14 years 6 months ago
Protein identification as an information retrieval problem
We present the first interdisciplinary work on transforming a popular problem in proteomics, i.e. protein identification from tandem mass spectra, to an Information Retrieval (IR)...
Yiming Yang, Subramaniam Ganapathy, Abhay Harpale
PKDD
2009
Springer
118views Data Mining» more  PKDD 2009»
14 years 6 months ago
Protein Identification from Tandem Mass Spectra with Probabilistic Language Modeling
This paper presents an interdisciplinary investigation of statistical information retrieval (IR) techniques for protein identification from tandem mass spectra, a challenging probl...
Yiming Yang, Abhay Harpale, Subramaniam Ganapathy