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SPIRE
2010
Springer
13 years 8 months ago
Identifying SNPs without a Reference Genome by Comparing Raw Reads
Next generation sequencing (NGS) technologies are being applied to many fields of biology, notably to survey the polymorphism across individuals of a species. However, while single...
Pierre Peterlongo, Nicolas Schnel, Nadia Pisanti, ...
FPL
2010
Springer
188views Hardware» more  FPL 2010»
13 years 9 months ago
SeqHive: A Reconfigurable Computer Cluster for Genome Re-sequencing
We demonstrate how Field Programmable Gate Arrays (FPGAs) may be used to address the computing challenges associated with assembling genome sequences from recent ultra-high-through...
Kristian Stevens, Henry Chen, Terry Filiba, Peter ...
BMCBI
2008
116views more  BMCBI 2008»
13 years 11 months ago
Clustering exact matches of pairwise sequence alignments by weighted linear regression
Background: At intermediate stages of genome assembly projects, when a number of contigs have been generated and their validity needs to be verified, it is desirable to align thes...
Alvaro J. González, Li Liao
BMCBI
2010
148views more  BMCBI 2010»
13 years 11 months ago
Calling SNPs without a reference sequence
Background: The most common application for the next-generation sequencing technologies is resequencing, where short reads from the genome of an individual are aligned to a refere...
Aakrosh Ratan, Yu Zhang, Vanessa M. Hayes, Stephan...
SAC
2010
ACM
13 years 11 months ago
FANGS: high speed sequence mapping for next generation sequencers
Next Generation Sequencing machines are generating millions of short DNA sequences (reads) everyday. There is a need for efficient algorithms to map these sequences to the referen...
Sanchit Misra, Ramanathan Narayanan, Simon Lin, Al...