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    SCFBM
    2008
    87views more  SCFBM 2008»
    Analysis by siRNA_profile program displays novel thermodynamic characteristics of highly functional siRNA molecules
    13 years 11 months ago
    Analysis by siRNA_profile program displays novel thermodynamic characteristics of highly functional siRNA molecules
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    Objective: Here we report the improved results of a new siRNA design program and analysis tool called siRNA_profile that reveals an additional criterion for bioinformatic search o...
    Pirkko Muhonen, Ranga N. Parthasarathy, Anthony J....
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    BMCBI
    2006
    130views more  BMCBI 2006»
    An accurate and interpretable model for siRNA efficacy prediction
    13 years 11 months ago
    An accurate and interpretable model for siRNA efficacy prediction
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    Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional s...
    Jean-Philippe Vert, Nicolas Foveau, Christian Laja...
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    BMCBI
    2006
    72views more  BMCBI 2006»
    Selecting effective siRNA sequences by using radial basis function network and decision tree learning
    13 years 11 months ago
    Selecting effective siRNA sequences by using radial basis function network and decision tree learning
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    Background: Although short interfering RNA (siRNA) has been widely used for studying gene functions in mammalian cells, its gene silencing efficacy varies markedly and there are o...
    Shigeru Takasaki, Yoshihiro Kawamura, Akihiko Kona...
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    BMCBI
    2007
    159views more  BMCBI 2007»
    sIR: siRNA Information Resource, a web-based tool for siRNA sequence design and analysis and an open access siRNA database
    13 years 11 months ago
    sIR: siRNA Information Resource, a web-based tool for siRNA sequence design and analysis and an open access siRNA database
    Download  www.biomedcentral.com
    Background: RNA interference has revolutionized our ability to study the effects of altering the expression of single genes in mammalian (and other) cells through targeted knockdo...
    Jyoti K. Shah, Harold R. Garner, Michael A. White,...
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