— Probe defects are a major source of noise in gene expression studies. While existing approaches detect noisy probes based on external information such as genomic alignments, we...
Leo Lahti, Laura Elo, Tero Aittokallio, Samuel Kas...
—Constructing accurate computational models that explain how ions permeate through a biological ion channel is an important problem in biophysics and drug design. Brownian dynami...
—Protein identification is a key and essential step in mass spectrometry (MS) based proteome research. To date, there are many protein identification strategies that employ eithe...
—In this paper, we propose a communication model of evolution and investigate its information-theoretic bounds. The process of evolution is modeled as the retransmission of infor...
Stochastic models such as hidden Markov models or stochastic context free grammars can fail to return the correct, maximum likelihood solution in the case of semantic ambiguity. T...
Recent experimental advances facilitate the collection of time series data that indicate which genes in a cell are expressed. This paper proposes an efficient method to generate th...
Nathan A. Barker, Chris J. Myers, Hiroyuki Kuwahar...
A TOPS diagram is a simplified description of the topology of a protein using a graph where nodes are α-helices and β-strands, and edges correspond to chirality relations and p...
: Extraction of meaningful information from large experimental datasets is a key element of bioinformatics research. One of the challenges is to identify genomic markers in Hepatit...
Kwong-Sak Leung, Kin-Hong Lee, Jin Feng Wang, Eddi...
—We study the problem of merging genetic maps, when the individual genetic maps are given as directed acyclic graphs. The computational problem is to build a consensus map, which...
—Pre-bond testing of 3-D stacked integrated circuits (ICs) involves testing each individual die before bonding. The overall yield of 3-D ICs improves with pre-bond testability be...
Xin Zhao, Dean L. Lewis, Hsien-Hsin S. Lee, Sung K...