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CONCURRENCY
2010
75views more  CONCURRENCY 2010»
13 years 11 months ago
An Open Source performance tools software suite for scientific computing
With the rapid replacement of closed, homogeneous, proprietary HPC systems by heterogeneous, Linux-MPI cluster systems, the state of performance monitoring and analysis tools has ...
Philip J. Mucci, Tushar Mohan
BMCBI
2008
98views more  BMCBI 2008»
13 years 11 months ago
MTAP: The Motif Tool Assessment Platform
Background: In recent years, substantial effort has been applied to de novo regulatory motif discovery. At this time, more than 150 software tools exist to detect regulatory bindi...
Daniel Quest, Kathryn Dempsey, Mohammad Shafiullah...
BMCBI
2008
115views more  BMCBI 2008»
13 years 11 months ago
Systems biology driven software design for the research enterprise
Background: In systems biology, and many other areas of research, there is a need for the interoperability of tools and data sources that were not originally designed to be integr...
John Boyle, Christopher C. Cavnor, Sarah A. Killco...
BMCBI
2007
186views more  BMCBI 2007»
13 years 11 months ago
GeneBins: a database for classifying gene expression data, with application to plant genome arrays
Background: To interpret microarray experiments, several ontological analysis tools have been developed. However, current tools are limited to specific organisms. Results: We deve...
Nicolas Goffard, Georg Weiller
BMCBI
2008
108views more  BMCBI 2008»
13 years 11 months ago
Signature Evaluation Tool (SET): a Java-based tool to evaluate and visualize the sample discrimination abilities of gene express
Background: The identification of specific gene expression signature for distinguishing sample groups is a dominant field in cancer research. Although a number of tools have been ...
Chih-Hung Jen, Tsun-Po Yang, Chien-Yi Tung, Shu-Ha...
BMCBI
2010
115views more  BMCBI 2010»
13 years 11 months ago
Non-coding RNA detection methods combined to improve usability, reproducibility and precision
Background: Non-coding RNAs gain more attention as their diverse roles in many cellular processes are discovered. At the same time, the need for efficient computational prediction...
Peter Raasch, Ulf Schmitz, Nadja Patenge, Julio Ve...
BMCBI
2007
136views more  BMCBI 2007»
13 years 11 months ago
Genomorama: genome visualization and analysis
Background: The ability to visualize genomic features and design experimental assays that can target specific regions of a genome is essential for modern biology. To assist in the...
Jason D. Gans, Murray Wolinsky
BMCBI
2008
89views more  BMCBI 2008»
13 years 11 months ago
R/parallel - speeding up bioinformatics analysis with R
Background: R is the preferred tool for statistical analysis of many bioinformaticians due in part to the increasing number of freely available analytical methods. Such methods ca...
Gonzalo Vera, Ritsert C. Jansen, Remo Suppi
BMCBI
2010
175views more  BMCBI 2010»
13 years 11 months ago
The BridgeDb framework: standardized access to gene, protein and metabolite identifier mapping services
Background: Many complementary solutions are available for the identifier mapping problem. This creates an opportunity for bioinformatics tool developers. Tools can be made to fle...
Martijn P. van Iersel, Alexander R. Pico, Thomas K...
BMCBI
2010
118views more  BMCBI 2010»
13 years 11 months ago
Towards realistic benchmarks for multiple alignments of non-coding sequences
Background: With the continued development of new computational tools for multiple sequence alignment, it is necessary today to develop benchmarks that aid the selection of the mo...
Jaebum Kim, Saurabh Sinha