Visualization of Lattice-Based Protein Folding Simulations

Analysis of the spacial structure of proteins including folding processes is a challenge for modern bioinformatics. Due to limited experimental access to folding processes, computer simulations are a standard approach. Since realistic continuous (all-atom) simulations are far too expensive, lattice based protein folding simulations are a common coarse-graining. In this paper, we present a visualization tool for lattice based protein folding simulations. The system is based on Shneiderman’s mantra ”Overview first, zoom and filter, details on demand” and uses a collection of information visualization techniques including multiple views, focus+context and table lenses which have been tailored towards our data. We demonstrate the potential of information visualization techniques for providing insight into such simulations. Keywords— Information visualization, multiple views, overview+detail, design guidelines, focus+context.

• Type: Conference
• Year: 2006
• Where: IV
• Authors: Sebastian Potzsch, Gerik Scheuermann, Peter F. Stadler, Michael T. Wolfinger, Christoph Flamm
• Keywords: Information Technology, Information Visualization Techniques, IV 2006, Lattice Based Protein, Protein Folding Simulations