A Microfluidic Device for DNA Tile Self-assembly

In order to self-assemble desired DNA nanostructure, it is necessary to suppress assembly errors caused by fluctuations of temperature and concentration. We propose a microfluidic device to directly control such environmental parameters of DNA self-assembly. In this paper, some experimental results concerned with key processes of self-assembly in the device, such as immobilizing DNA strands in a reaction chamber and relation rate of hybridization under flow condition are reported.

• Type: Conference
• Year: 2005
• Where: DNA
• Authors: Koutaro Somei, Shohei Kaneda, Teruo Fujii, Satoshi Murata
• Keywords: DNA 2005, DNA Nanostructure, DNA Self-assembly, Microfluidic Device