Genome Halving

The Genome Halving Problem is motivated by the whole genome duplication events in molecular evolution that double the gene content of a genome and result in a perfect duplicated genome that contains two identical copies of each chromosome. The genome then becomes a subject to rearrangements resulting in some rearranged duplicated genome. The Genome Halving Problem (first introduced and solved by Nadia El-Mabrouk and David Sankoff) is to reconstruct the ancestral pre-duplicated genome from the rearranged duplicated genome. The El-Mabrouk

• Type: Conference
• Year: 1998
• Where: CPM
• Authors: Nadia El-Mabrouk, Joseph H. Nadeau, David Sankoff
• Keywords: Combinatorics, CPM 1998, Duplicated Genomes, Genome Duplications, Genome Halving Problem