The objective of this research is to present the symbiosis concept that integrates creativity and the recent research issues in affective response to products shapes. The major idea behind this study is systematically using affective response and design axiomatic in rational way through creativity approach that support on creativity stimulation for current highly competitive market. The practicality of the proposed methodology involved affective response measurable system that based on Semantic Differential (SD) method and interrelated computational regulation, creativity approach that based on Sensuous Association Method (SAM) and Creativity-Based Design Process (CBDP), and integrated mechanism using Axiomatic Design (AD) method.