Hierarchy-based 3-D Visualization of Homologous Gene Expression across Different Organisms

With the explosive growth of proteomic and expression data of homologous genes, it becomes necessary to explore new methods to visualize and analyze related gene expression data to investigate inherent similarities and differences of different organisms. We present a new approach to visualize complex datasets representing gene expression and pathway models from different data sources in a 3?D hierarchical view space according to a hierarchical data model. With chicken and human as model organisms, we describe our approach to visualize genomic data of different organisms in a hierarchical structure. In our visualization approach, not only the text data but also diagram images of pathways and chromosome maps of different organisms can be visualized within a 3?D hierarchical view space such that data of different organisms can be compared visually. CR Categories: J.3 [Life and Medical Sciences]: Biology and genetics, and Medical information systems; I.3.8 [Computer Graphics]: Application...

• Type: Conference
• Year: 2006
• Where: VIS
• Authors: Li Jin, Karl V. Steiner, Carl J. Schmidt, Keith S. Decker
• Keywords: Gene Expression Data, Hierarchical Data Model, Hierarchical View Space, IEEE Visualization, VIS 2006, Visualization