Ontologies are central to the architecture of the Semantic Web, the next generation Web that is currently under active development. We have developed ImageSpace, an image ontology creation and annotation tool that features (1) full support for the standard web ontology language DAML+OIL; (2) image ontology creation, image annotation and display in one integrated framework; (3) ontology consistency assurance; and (4) storing ontologies in relational databases. It is expected that the availability of such a tool will greatly facilitate the creation of image repositories as islands of the Semantic Web.