Genome annotation projects may produce wrong results since they may be based on obsolete data or wrong models. This work aims to develop an automatic re-annotation system that use agents to perform repetitive tasks and reports the results to the user. These tasks involve BLAST searchs on biological databases (GenBank) and the use of detection tools (Genemark and Glimmer) to identify new ORFs. Several agents execute these tools and combine their results to produce a list of ORFs that are sent back to the user. The goal of this work is to reduce the manual work develop on re-annotation, executing most tasks automatically by computational tools.
Leonardo Vianna do Nascimento, Ana L. C. Bazzan