Optimal treatments for photodynamic therapy

Photodynamic therapy is a complex treatment for neoplastic diseases that uses the light-harvesting properties of a photosensitizer. The treatment depends on the amount of photosensitizer in the tissue and on the amount of light that is focused on the targeted area. We use a pharmacokinetic model to represent a photosensitizer's movement through the anatomy and design treatments with a linear program. This technique allows us to investigate how a treatment's success varies over time.

• Type: Conference
• Year: 2008
• Where: 4OR
• Authors: A. Holder, D. Llagostera
• Keywords: 4OR 2008, Light-harvesting Properties, Neoplastic Diseases, Photodynamic Therapy