Alternative contingency table measures improve the power and detection of multifactor dimensionality reduction

Background: Multifactor Dimensionality Reduction (MDR) has been introduced previously as a non-parametric statistical method for detecting gene-gene interactions. MDR performs a dimensional reduction by assigning multi-locus genotypes to either high- or low-risk groups and measuring the percentage of cases and controls incorrectly labelled by this classification

• Type: Journal
• Year: 2008
• Where: BMCBI
• Authors: William S. Bush, Todd L. Edwards, Scott M. Dudek, Brett A. McKinney, Marylyn D. Ritchie
• Keywords: BMCBI 2008, Classification Error, Gene-gene Interaction, Two-way Contingency Table