In silico modelling of hormone response elements

Background: An important step in understanding the conditions that specify gene expression is the recognition of gene regulatory elements. Due to high diversity of different types of transcription factors and their DNA binding preferences, it is a challenging problem to establish an accurate model for recognition of functional regulatory elements in promoters of eukaryotic genes. Results: We present a method for precise prediction of a large group of transcription factor binding sites

• Type: Journal
• Year: 2006
• Where: BMCBI
• Authors: Maria Stepanova, Feng Lin, Valerie C.-L. Lin
• Keywords: BMCBI 2006, Hormone Response Elements, Steroid Hormone Response, Steroid Hormones