Novel methods for secondary structure determination using low wavelength (VUV) circular dichroism spectroscopic data

Background: Circular Dichroism (CD) spectroscopy is a widely used method for studying protein structures in solution. Modern synchrotron radiation CD (SRCD) instruments have considerably higher photon fluxes than do conventional lab-based CD instruments, and hence have the ability to routinely measure CD data to much lower wavelengths. Recently a new reference dataset of SRCD spectra of proteins of known structure, designed to cover secondary structure and fold space, has been produced which includes low wavelength (vacuum ultraviolet

• Type: Journal
• Year: 2006
• Where: BMCBI
• Authors: Jonathan G. Lees, Andrew J. Miles, Robert W. Janes, B. A. Wallace
• Keywords: BMCBI 2006, CD Data, Low Wavelength, Secondary Structure