We investigate the decoding problem of Reed-Solomon (RS) Codes, also known as the Polynomial Reconstruction Problem (PR), from a cryptographic hardness perspective. Namely, we deal with PR instances with parameter choices for which decoding is not known to be feasibly solvable and where part of the solution polynomial is the hidden input. We put forth a natural decisional intractability assumption that relates to this decoding problem: distinguishing between a single randomly chosen error-location and a single randomly chosen non-error location for a given corrupted RS codeword with random noise. We prove that under this assumption, PR-instances are entirely pseudorandom, i.e., they are indistinguishable from random vectors over the underlying finite field. Moreover, under the same assumption we show that it is hard to extract any partial information related to the hidden input encoded by the corrupted PR-instance, i.e., PR-instances hide their message polynomial solution in the seman...