InterferenceAnalyzer: Tools for the analysis and simulation of multi-locus genetic data

Background: Good statistical models for analyzing and simulating multilocus recombination data exist but are not accessible to many biologists because their use requires reasonably sophisticated mathematical and computational implementation. While some labs have direct access to statisticians or programmers competent to carry out such analyses, many labs do not. We have created a platform independent application with an easy-to-use graphical user interface that will carry out such analyses including the simulations needed to bootstrap confidence intervals for the parameters of interest. This software should make multi-locus techniques accessible to labs that previously relied on less powerful and potentially statistically confounded single interval or double interval techniques. Results: We introduce InterferenceAnalyzer, an implementation with a user-friendly graphical interface incorporating previously developed algorithms for the analysis and simulation of multilocus recombination ...

• Type: Journal
• Year: 2005
• Where: BMCBI
• Authors: Lalitha Viswanath, Elizabeth A. Housworth
• Keywords: BMCBI 2005, Multilocus Recombination Data, Multilocus Tetrad Data, Tetrad Data