Making sense of microarray data distributions

Motivation: Typical analysis of microarray data has focused on spot by spot comparisons within a single organism. Less analysis has been done on the comparison of the entire distribution of spot intensities between experiments and between organisms. Results: Here we show that mRNA transcription data from a wide range of organisms and measured with a range of experimental platforms show close agreement with Benford's law (Benford, Proc. Am. Phil. Soc., 78, 551

• Type: Journal
• Year: 2002
• Where: BIOINFORMATICS
• Authors: David C. Hoyle, Magnus Rattray, Ray Jupp, Andy Brass
• Keywords: BIOINFORMATICS 2002, MRNA Transcription Data, Spot Comparisons, Spot Intensities